The integration of Deep Learning (DL) techniques with the Internet of Things (IoT) has emerged as a transformative paradigm in the advancement of smart healthcare systems. Numerous recent studies have investigated the convergence of these technologies, demonstrating their potential in improving healthcare delivery, patient monitoring, and clinical decision-making. The ongoing evolution of Industry 5.0 in parallel with the deployment of 5G communication networks has further facilitated the development of intelligent, cost-effective, and highly responsive sensors. These innovations enable continuous and real-time monitoring of patients’ health conditions, a capability that was not feasible within the constraints of traditional healthcare models. Smart health monitoring systems have thus introduced significant improvements in terms of speed, affordability, reliability, and accessibility of medical services, particularly in remote or underserved regions. Moreover, the application of Deep Learning and Machine Learning algorithms in health data analysis has played a pivotal role in achieving preventive healthcare, reducing mortality risks, and enabling personalized treatment strategies. Such methods have also enhanced the early detection of chronic diseases, which previously posed considerable diagnostic challenges. To further optimize scalability and cost-efficiency, cloud computing and distributed storage solutions have been incorporated, ensuring secure and real-time data availability. This review therefore provides a comprehensive perspective on smart healthcare innovations, emphasizing the role of intelligent systems, recent advancements, and persisting challenges in the domain of digital health monitoring.